IHPE – GOURBAL Benjamin

BenIHPE UMR 5244
Université de Perpignan via Domitia
52 Avenue Paul Alduy
F-66860 Perpignan Cedex
Tel +33(0)4-68-66-21-88
Fax +33(0)4-68-66-22-81
email: benjamin.gourbal@univ-perp.fr

GRADE : Professeur, Université de Perpignan Via Domitia (HDR)
EQUIPE : 2MAP
ENCADREMENT DE THESE ACTUEL :
Sarah DAMETTO (2022-)
Chaimaa SABRI (2024-)
RESPONSABILITES :
– Co-directeur de l’Ecole Doctorale 305 Energie Environnement de l’UPVD
– Membre élu au Conseil de Laboratoire (Collège A Chercheurs et Enseignants-Chercheurs, sous-collège permanents)
– Co-Responsable de l’équipe 2MAP

RESEAUX SOCIAUX SCIENTIFIQUES :

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DOMAINE D’EXPERTISE-RECHERCHE :
Mon activité scientifique porte un intérêt particulier à l’évolution des processus immunitaires, et la compréhension de la réponse immunitaire innée et sa régulation chez les invertébrés dans le modèle: mollusque Biomphalaria glabrata et son trématode parasite Schistosoma mansoni. Dans ce modèle, j’étudie les mécanismes qui déterminent le polymorphisme de compatibilité, la spécificité et la régulation de la réponse immunitaire innée. Je mène également des approches sur les mécanismes moléculaires de la réponse immunitaire mémoire ou priming chez B. glabrata. J’ai développé récemment des collaborations où cette question sera abordée dans le priming immunitaire antiviral chez le mollusque Crassostrea gigas et dans le priming immunitaire trans-générationnel (PITG) chez le coléoptère Tenebrio molitor.
Pour réponde à ces questions, différentes approches moléculaires comparatives ont été développées aux niveaux : génomique (DNAseq), transcriptomique (RNASeq, QRT-PCR) et protéique (enrichissement, 2D-DIGE, interactome). Nous développons également des approches fonctionnelles : protéines recombinantes, ARN interférence, culture in vitro.

DISTINCTION :
2020 : Nommé Chevalier de l’Ordre National du Mérite

CURSUS :
2022 Professeur Université de Perpignan via Domitia
2012 Habilitation à Diriger les Recherches HDR « Interactions immunobiologiques dans le modèle Biomphalaria glabrata/Schistsosoma mansoni : aspects évolutifs et moléculaires du polymorphisme de compatibilité, de l’imunité innée et de la mémoire immunitaire » (Université de Perpignan via Domitia)
2005-présent Maître de Conférences (Université de Perpignan via Domitia)
2003-2005 Post-Doctorat (Centre de Recherche en Infectiologie, CHU Laval de Québec, Canada)
1999-2002 Doctorat (Université de Montpellier II)
1998-1999 DEA Parasitologie (Université de Montpellier II)

PUBLICATIONS :


116 documents

Articles dans une revue73 document

  • Pierre Poteaux, Chantal Ripoll, Amélie Sarrazin, Marie-Pierre Blanchard, Anne Guillou-Duvoid, et al.. Breaking Biomphalaria black box by in situ revelation of fluorescent Schistosoma mansoni parasites. Fish and Shellfish Immunology, 2024, 153, pp.109800. ⟨10.1016/j.fsi.2024.109800⟩. ⟨hal-04683439⟩
  • Sébastien de la Forest Divonne, Juliette Pouzadoux, Océane Romatif, Caroline Montagnani, Guillaume Mitta, et al.. Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations. eLife, 2024, ⟨10.1101/2024.07.19.604245⟩. ⟨hal-04869462⟩
  • Caroline Montagnani, Benjamin Morga, Beatriz Novoa, Benjamin Gourbal, Amaro Saco, et al.. Trained immunity: Perspectives for disease control strategy in marine mollusc aquaculture. Reviews in Aquaculture, 2024, 16 (4), pp.1472-1498. ⟨10.1111/raq.12906⟩. ⟨hal-04565659⟩
  • Elodie Simphor, Anne Rognon, Emmanuel Vignal, Sylvain Henry, Jean-François Allienne, et al.. Combining a transcriptomic approach and a targeted metabolomics approach for deciphering the molecular bases of compatibility phenotype in the snail Biomphalaria glabrata toward Schistosoma mansoni.. Acta Tropica, 2024, 255, pp.107212. ⟨10.1016/j.actatropica.2024.107212⟩. ⟨hal-04555554⟩
  • Pierre Poteaux, Benjamin Gourbal, David Duval. Time series analysis of tegument ultrastructure of in vitro transformed miracidium to mother sporocyst of the human parasite Schistosoma mansoni. Acta Tropica, 2023, 240, pp.106840. ⟨10.1016/j.actatropica.2023.106840⟩. ⟨hal-03974738⟩
  • Camille Clerissi, Camille Huot, Anaïs Portet, Benjamin Gourbal, Eve Toulza. Covariation between microeukaryotes and bacteria associated with Planorbidae snails. PeerJ, 2023, 11, pp.e16639. ⟨10.7717/peerj.16639⟩. ⟨hal-04373549⟩
  • David Duval, Pierre Poteaux, Benjamin Gourbal, Anne Rognon, Ronaldo de Carvalho Augusto. Fluorescent non transgenic schistosoma to decipher host-parasite phenotype compatibility. Frontiers in Immunology, 2023, 14, pp.1293009. ⟨10.3389/fimmu.2023.1293009⟩. ⟨hal-04324556⟩
  • Philippe Douchet, Benjamin Gourbal, Eric Loker, Olivier Rey. Schistosoma transmission: scaling-up competence from hosts to ecosystems. Trends in Parasitology, In press, ⟨10.1016/j.pt.2023.04.001⟩. ⟨hal-04097261⟩
  • I A Orlov, G L Ataev, Benjamin Gourbal, A S Tokmakova, A V Bobrovskaya, et al.. The transcriptomic analysis of Planorbarius corneus hemocytes (Gastropoda) naturally infected with Bilharziella polonica (Schistosomatidae). Developmental and Comparative Immunology, 2023, 140, pp.104607. ⟨10.1016/j.dci.2022.104607⟩. ⟨hal-04000378⟩
  • Remi Pichon, Silvain Pinaud, Emmanuel Vignal, Cristian Chaparro, Marine Pratlong, et al.. Single cell RNA sequencing reveals hemocyte heterogeneity in Biomphalaria glabrata: Plasticity over diversity. Frontiers in Immunology, 2022, 13, pp.956871. ⟨10.3389/fimmu.2022.956871⟩. ⟨hal-03772193⟩
  • Annia Alba, Antonio Vázquez, Jorge Sánchez, Benjamin Gourbal. Immunological Resistance of Pseudosuccinea columella Snails From Cuba to Fasciola hepatica (Trematoda) Infection: What We Know and Where We Go on Comparative Molecular and Mechanistic Immunobiology, Ecology and Evolution. Frontiers in Immunology, 2022, 13, pp.794186. ⟨10.3389/fimmu.2022.794186⟩. ⟨hal-03608737⟩
  • Anaïs Portet, Eve Toulza, Ana Lokmer, Camille Huot, David Duval, et al.. Experimental Infection of the Biomphalaria glabrata Vector Snail by Schistosoma mansoni Parasites Drives Snail Microbiota Dysbiosis. Microorganisms, 2021, 9 (5), pp.1084. ⟨10.3390/microorganisms9051084⟩. ⟨hal-03315096⟩
  • Silvain Pinaud, Guillaume Tetreau, Pierre Poteaux, Richard Galinier, Cristian Chaparro, et al.. New insights into biomphalysin gene family diversification in the vector snail Biomphalaria glabrata. Frontiers in Immunology, 2021, 12, pp.635131. ⟨10.3389/fimmu.2021.635131⟩. ⟨hal-03219003⟩
  • Anaïs Portet, Richard Galinier, Damien Lassalle, Alexandre Faille, Benjamin Gourbal, et al.. Hemocyte siRNA uptake is increased by 5′ cholesterol-TEG addition in Biomphalaria glabrata , snail vector of schistosome. PeerJ, 2021, 9, pp.e10895. ⟨10.7717/peerj.10895⟩. ⟨hal-03163875⟩
  • Yohann Le Govic, Benjamin Gourbal, Jérôme Boissier. Booming Omics in Schistosoma. Trends in Parasitology, 2020, 37 (1), pp.6-8. ⟨10.1016/j.pt.2020.10.010⟩. ⟨hal-03001273⟩
  • Ronaldo de Carvalho Augusto, Nadjiya Merad, Anne Rognon, Benjamin Gourbal, Cédric Bertrand, et al.. Molluscicidal and parasiticidal activities of Eryngium triquetrum essential oil on Schistosoma mansoni and its intermediate snail host Biomphalaria glabrata, a double impact. Parasites & Vectors, 2020, ⟨10.1186/s13071-020-04367-w⟩. ⟨hal-02974798⟩
  • Maxime Lafont, Agnès Vergnes, Jeremie Vidal-Dupiol, Julien de Lorgeril, Yannick Guéguen, et al.. A Sustained Immune Response Supports Long-Term Antiviral Immune Priming in the Pacific Oyster, Crassostrea gigas. mBio, 2020, 11 (2), pp.e02777-19. ⟨10.1128/mBio.02777-19⟩. ⟨hal-02527469⟩
  • Damien Lassalle, Guillaume Tetreau, Silvain Pinaud, Richard Galinier, Neil Crickmore, et al.. Glabralysins, Potential New β-Pore-Forming Toxin Family Members from the Schistosomiasis Vector Snail Biomphalaria glabrata. Genes, 2020, 11 (1), pp.65. ⟨10.3390/genes11010065⟩. ⟨hal-02431962⟩
  • David Duval, Remi Pichon, Damien Lassalle, Maud Laffitte, Benjamin Gourbal, et al.. A New Assessment of Thioester-Containing Proteins Diversity of the Freshwater Snail Biomphalaria glabrata. Genes, 2020, 11, pp.69. ⟨10.3390/genes11010069⟩. ⟨hal-02431935⟩
  • Annia Alba, David Duval, Jorge Sánchez, Ana B Perez, Silvain Pinaud, et al.. The immunobiological interplay between Pseudosuccinea columella resistant/susceptible snails with Fasciola hepatica: Hemocytes in the spotlight. Developmental and Comparative Immunology, 2020, 102, pp.103485. ⟨10.1016/j.dci.2019.103485⟩. ⟨hal-02279344⟩
  • Camille Huot, Camille Clerissi, Benjamin Gourbal, Richard Galinier, David Duval, et al.. Schistosomiasis vector snails and their microbiota display a phylosymbiosis pattern. Frontiers in Microbiology, In press, ⟨10.3389/fmicb.2019.03092⟩. ⟨hal-02440210⟩
  • Guillaume Tetreau, Julien Dhinaut, Richard Galinier, Pascaline Audant-Lacour, Sébastien Voisin, et al.. Deciphering the molecular mechanisms of mother-to-egg immune protection in the mealworm beetle Tenebrio molitor. PLoS Pathogens, 2020, 16 (10), pp.e1008935. ⟨10.1371/journal.ppat.1008935⟩. ⟨hal-02994654⟩
  • Anaïs Portet, Silvain Pinaud, Cristian Chaparro, Richard Galinier, Nolwenn M. Dheilly, et al.. Sympatric versus allopatric evolutionary contexts shape differential immune response in Biomphalaria / Schistosoma interaction. PLoS Pathogens, 2019, 15 (3), pp.e1007647. ⟨10.1371/journal.ppat.1007647⟩. ⟨hal-02076267⟩
  • Silvain Pinaud, Anaïs Portet, Jean-François Allienne, Lucid Belmudes, Cécile Saint-Beat, et al.. Molecular characterisation of immunological memory following homologous or heterologous challenges in the schistosomiasis vector snail, Biomphalaria glabrata. Developmental and Comparative Immunology, 2019, 92, pp.238-252. ⟨10.1016/j.dci.2018.12.001⟩. ⟨hal-01952235⟩
  • Annia Alba, Antonio Vázquez, Jorge Sánchez, Manon Lounnas, Jean-Pierre Pointier, et al.. Patterns of distribution, population genetics and ecological requirements of field-occurring resistant and susceptible Pseudosuccinea columella snails to Fasciola hepatica in Cuba. Scientific Reports, 2019, 9, pp.14359. ⟨10.1038/s41598-019-50894-7⟩. ⟨hal-03655466v2⟩
  • Guillaume Tetreau, Julien Dhinaut, Benjamin Gourbal, Yannick Moret. Trans-generational Immune Priming in Invertebrates: Current Knowledge and Future Prospects. Frontiers in Immunology, 2019, 10, pp.1938. ⟨10.3389/fimmu.2019.01938⟩. ⟨hal-02273516⟩
  • Annia Alba, Guillaume Tetreau, Cristian Chaparro, Jorge Sánchez, Antonio Vázquez, et al.. Natural resistance to Fasciola hepatica (Trematoda) in Pseudosuccinea columella snails: A review from literature and insights from comparative “omic” analyses. Developmental and Comparative Immunology, 2019, 101, pp.103463. ⟨10.1016/j.dci.2019.103463⟩. ⟨hal-02279394⟩
  • Annia Alba, Antonio Vázquez, Jorge Sánchez, David Duval, Hilda Hernández, et al.. Fasciola hepatica-Pseudosuccinea columella interaction: effect of increasing parasite doses, successive exposures and geographical origin on the infection outcome of susceptible and naturally-resistant snails from Cuba. Parasites & Vectors, 2018, 11, pp.559. ⟨10.1186/s13071-018-3155-3⟩. ⟨hal-01912747⟩
  • Anaïs Portet, Richard Galinier, Silvain Pinaud, Julien Portela, Fanny Nowacki, et al.. BgTEP: an antiprotease involved in innate immune sensing in Biomphalaria glabrata. Frontiers in Immunology, 2018, 9, pp.1206. ⟨10.1101/308130⟩. ⟨hal-01838951⟩
  • Euan R.O. Allan, Benjamin Gourbal, Camila Dores, Anaïs Portet, Christopher Bayne, et al.. Clearance of schistosome parasites by resistant genotypes at a single genomic region in Biomphalaria glabrata snails involves cellular components of the hemolymph. International Journal for Parasitology, 2018, 48 (5), pp.387 - 393. ⟨10.1016/j.ijpara.2017.08.008⟩. ⟨hal-01808560⟩
  • Benjamin Gourbal, Silvain Pinaud, Gerold Beckers, Jos W. M. van Der Meer, Uwe Conrath, et al.. Innate immune memory: An evolutionary perspective. Immunological Reviews, 2018, Immunologic Memory, 283 (1), pp.21-40. ⟨10.1111/imr.12647⟩. ⟨hal-01792968⟩
  • Maxime Lafont, Bruno Petton, Agnès Vergnes, Marianna Pauletto, Amélie Segarra, et al.. Long-lasting antiviral innate immune priming in the Lophotrochozoan Pacific oyster, Crassostrea gigas. Scientific Reports, 2017, 7, pp.13143. ⟨10.1038/s41598-017-13564-0⟩. ⟨hal-01632346⟩
  • Richard Galinier, Emmanuel Roger, Yves Moné, David Duval, Anaïs Portet, et al.. A multistrain approach to studying the mechanisms underlying compatibility in the interaction between Biomphalaria glabrata and Schistosoma mansoni. PLoS Neglected Tropical Diseases, 2017, 11 (3), pp.e0005398. ⟨10.1371/journal.pntd.0005398.s005⟩. ⟨hal-01511153⟩
  • Richard Galinier, Guillaume Tetreau, Anaïs Portet, Silvain Pinaud, David Duval, et al.. First characterization of viruses from freshwater snails of the genus Biomphalaria, the intermediate host of the parasite Schistosoma mansoni. Acta Tropica, 2017, 167, pp.196-203. ⟨10.1016/j.actatropica.2016.12.021⟩. ⟨hal-01435053⟩
  • Anaïs Portet, Silvain Pinaud, Guillaume Tetreau, Richard Galinier, Celine Cosseau, et al.. Integrated multi-omic analyses in Biomphalaria-Schistosoma dialogue reveal the immunobiological significance of FREP- Sm PoMuc interaction. Developmental and Comparative Immunology, 2017, 75, pp.16 - 27. ⟨10.1016/j.dci.2017.02.025⟩. ⟨hal-01598455⟩
  • C. Adema, L. Hillier, C. Jones, E.S. Loker, M. Knight, et al.. Whole genome analysis of a schistosomiasis-transmitting freshwater snail. Nature Communications, 2017, 8, pp.15451. ⟨10.1038/ncomms15451⟩. ⟨hal-01523953⟩
  • Guillaume Mitta, Benjamin Gourbal, Christoph Grunau, M. Knight, J.M. Bridger, et al.. The compatibility between Biomphalaria glabrata snails and Schistosoma mansoni: an increasingly complex puzzle. Advances in Parasitology, 2017, 97, pp.111-145. ⟨10.1016/bs.apar.2016.08.006⟩. ⟨hal-01511043⟩
  • Guillaume Tetreau, Silvain Pinaud, Anaïs Portet, Richard Galinier, Benjamin Gourbal, et al.. Specific Pathogen Recognition by Multiple Innate Immune Sensors in an Invertebrate. Frontiers in Immunology, 2017, 8, pp.1249. ⟨10.3389/fimmu.2017.01249⟩. ⟨hal-01729395⟩
  • Silvain Pinaud, Julien Portela, David Duval, Fanny Nowacki, Marie-Aude Olive, et al.. A shift from cellular to humoral responses contributes to innate immune memory in the vector snail $Biomphalaria\ glabrata$. PLoS Pathogens, 2016, 12 (1), pp.e1005361. ⟨10.1371/journal.ppat.1005361⟩. ⟨hal-03778962⟩
  • Nolwenn M. Dheilly, Fanny Maure, Marc Ravallec, Richard Galinier, Josée Doyon, et al.. Who is the puppet master? Replication of a parasitic wasp-associated virus correlates with host behaviour manipulation. Proceedings of the Royal Society B: Biological Sciences, 2015, 282 (1803), pp.20142773. ⟨10.1098/rspb.2014.2773⟩. ⟨hal-01141139⟩
  • Christine Coustau, Benjamin Gourbal, David Duval, T.P. Yoshino, C. M. Adema, et al.. Advances in gastropod immunity from the study of the interaction between the snail Biomphalaria glabrata and its parasites: A review of research progress over the last decade. Fish and Shellfish Immunology, 2015, 46 (1), pp.5-16. ⟨10.1016/j.fsi.2015.01.036⟩. ⟨hal-01162871⟩
  • David Duval, Richard Galinier, Gabriel Mouahid, Eve Toulza, Jean-François Allienne, et al.. A Novel Bacterial Pathogen of Biomphalaria glabrata: A Potential Weapon for Schistosomiasis Control?. PLoS Neglected Tropical Diseases, 2015, 9 (2), pp.e0003489. ⟨10.1371/journal.pntd.0003489.s002⟩. ⟨hal-01162649⟩
  • Audrey Sophie Vanhove, Marylise Duperthuy, Guillaume M Charrière, Frédérique Le Roux, David Goudenège, et al.. Outer membrane vesicles are vehicles for the delivery of Vibrio tasmaniensis virulence factors to oyster immune cells.. Environmental Microbiology, 2015, Pathogen ecology and lifestyles, 17 (4), pp.1152-1165. ⟨10.1111/1462-2920.12535⟩. ⟨halsde-01054322⟩
  • Nolwenn M. Dheilly, David Duval, Gabriel Mouahid, Rémi Emans, Jean-François Allienne, et al.. A family of variable immunoglobulin and lectin domain containing molecules in the snail Biomphalaria glabrata. Developmental and Comparative Immunology, 2015, 48 (1), pp.234-243. ⟨10.1016/j.dci.2014.10.009⟩. ⟨hal-01082870⟩
  • A. Theron, Anne Rognon, Benjamin Gourbal, G. Mitta. Multi-parasite host susceptibility and multi-host parasite infectivity: A new approach of the Biomphalaria glabrata/Schistosoma mansoni compatibility polymorphism.. Infection, Genetics and Evolution, 2014, 26, pp.80-88. ⟨10.1016/j.meegid.2014.04.025⟩. ⟨halsde-00998747⟩
  • Nolwenn M. Dheilly, Coen Adema, David A Raftos, Benjamin Gourbal, Christoph Grunau, et al.. No more non-model species: The promise of next generation sequencing for comparative immunology.. Developmental and Comparative Immunology, 2014, 45 (1), pp.56-66. ⟨10.1016/j.dci.2014.01.022⟩. ⟨hal-03779118⟩
  • Olga Lucia Baron, Pieter van West, Benoit Industri, Michel Ponchet, Géraldine Dubreuil, et al.. Parental Transfer of the Antimicrobial Protein LBP/BPI Protects Biomphalaria glabrata Eggs against Oomycete Infections.. PLoS Pathogens, 2013, 9 (12), pp.e1003792. ⟨10.1371/journal.ppat.1003792⟩. ⟨hal-00938929⟩
  • Richard Galinier, Julien Portela, Yves Moné, Jean-François Allienne, Hélène Henri, et al.. Biomphalysin, a new β pore-forming toxin involved in Biomphalaria glabrata immune defense against Schistosoma mansoni.. PLoS Pathogens, 2013, 9 (3), pp.e1003216. ⟨10.1371/journal.ppat.1003216⟩. ⟨halsde-00823685⟩
  • Julien Portela, David Duval, Anne Rognon, Richard Galinier, Jérôme Boissier, et al.. Evidence for Specific Genotype-Dependent Immune Priming in the Lophotrochozoan Biomphalaria glabrata Snail.. Journal of Innate Immunity, 2013, 5 (3), pp.261-276. ⟨10.1159/000345909⟩. ⟨halsde-00790554⟩
  • Julien Portela, Jérôme Boissier, Benjamin Gourbal, Vincent Pradines, Vincent Collière, et al.. Antischistosomal activity of trioxaquines: in vivo efficacy and mechanism of action on Schistosoma mansoni. PLoS Neglected Tropical Diseases, 2012, 6 (2), pp.e1474. ⟨10.1371/journal.pntd.0001474⟩. ⟨halsde-00670260⟩
  • Emeline Deleury, Géraldine Dubreuil, Namasivayam Elangovan, Eric Wajnberg, Jean-Marc Reichhart, et al.. Specific versus non-specific immune responses in an invertebrate species evidenced by a comparative de novo sequencing study.. PLoS ONE, 2012, 7 (3), pp.e32512. ⟨10.1371/journal.pone.0032512⟩. ⟨halsde-00700368⟩
  • G. Mitta, C. M. Adema, Benjamin Gourbal, E. S. Loker, A. Theron. Compatibility polymorphism in snail/schistosome interactions: From field to theory to molecular mechanisms.. Developmental and Comparative Immunology, 2011, 37 (1), pp.1-8. ⟨10.1016/j.dci.2011.09.002⟩. ⟨halsde-00631055⟩
  • Jean-François Allienne, André Théron, Benjamin Gourbal. Recovery of primary sporocysts in vivo in the Schistosoma mansoni/Biomphalaria glabrata model using a simple fixation method suitable for extraction of genomic DNA and RNA.. Experimental Parasitology, 2011, 129 (1), pp.11-16. ⟨10.1016/j.exppara.2011.06.003⟩. ⟨halsde-00612896⟩
  • Sophie Beltran, Benjamin Gourbal, Jérôme Boissier, David Duval, S. Kieffer-Jaquinod, et al.. Vertebrate host protective immunity drives genetic diversity and antigenic polymorphism in Schistosoma mansoni.. Journal of Evolutionary Biology, 2011, 24 (3), pp.554-72. ⟨10.1111/j.1420-9101.2010.02190.x⟩. ⟨halsde-00580773⟩
  • Yves Moné, Anne-Cécile Ribou, Celine Cosseau, David Duval, André Théron, et al.. An example of molecular co-evolution: Reactive oxygen species (ROS) and ROS scavenger levels in Schistosoma mansoni/Biomphalaria glabrata interactions.. International Journal for Parasitology, 2011, 41 (7), pp.721-730. ⟨10.1016/j.ijpara.2011.01.007⟩. ⟨halsde-00580768⟩
  • Yves Moné, Benjamin Gourbal, David Duval, Louis Du Pasquier, Sylvie Kieffer-Jaquinod, et al.. A large repertoire of parasite epitopes matched by a large repertoire of host immune receptors in an invertebrate host/parasite model. PLoS Neglected Tropical Diseases, 2010, 4 (9), pp.e813. ⟨10.1371/journal.pntd.0000813⟩. ⟨halsde-00515823⟩
  • Yves Moné, Guillaume Mitta, David Duval, Benjamin E F Gourbal. Effect of amphotericin B on the infection success of Schistosoma mansoni in Biomphalaria glabrata.. Experimental Parasitology, 2010, 125 (2), pp.70-5. ⟨10.1016/j.exppara.2009.12.024⟩. ⟨halsde-00495366⟩
  • Alvaro Baeza Garcia, Raymond J. Pierce, Benjamin Gourbal, Elisabeth Werkmeister, Dominique Colinet, et al.. Involvement of the cytokine MIF in the snail host immune response to the parasite Schistosoma mansoni.. PLoS Pathogens, 2010, 6 (9), pp.e1001115. ⟨10.1371/journal.ppat.1001115⟩. ⟨halsde-00608628⟩
  • C. Coustau, A. Baeza-Garcia, Benjamin Gourbal, A. Théron. Adaptation of Biomphalaria glabrata to foreign invaders. Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, 2009, 154 (1 suppl), pp.S33. ⟨10.1016/j.cbpa.2009.05.110⟩. ⟨halsde-00459182⟩
  • Benjamin Gourbal, Frédéric Guillou, G. Mitta, Pierre Sibille, A. Théron, et al.. Excretory-secretory products of larval Fasciola hepatica investigated using a two-dimensional proteomic approach. Molecular and Biochemical Parasitology, 2008, 161 (1), pp.63-66. ⟨10.1016/j.molbiopara.2008.05.002⟩. ⟨halsde-00332385⟩
  • K. El Fadili, M. Imbeault, N. Messier, G. Roy, Benjamin Gourbal, et al.. Modulation of gene expression in human macrophages threated with the anti-Leishmania pentavalent antimonial drug sodium stibogluconate. Antimicrobial Agents and Chemotherapy, 2008, 52 (2), pp.526-533. ⟨10.1128/AAC.01183-07⟩. ⟨halsde-00286375⟩
  • Emmanuel Roger, Christoph Grunau, Raymond J. Pierce, Hirohisa Hirai, Benjamin Gourbal, et al.. Controlled chaos of polymorphic mucins in a metazoan parasite (Schistosoma mansoni) interacting with its invertebrate host (Biomphalaria glabrata).. PLoS Neglected Tropical Diseases, 2008, 2 (11), pp.e330. ⟨10.1371/journal.pntd.0000330⟩. ⟨halsde-00344615⟩
  • A. Bouchut, Elise Roger, Benjamin Gourbal, Christoph Grunau, Christine Cousteau, et al.. The compatibility polymorphism in invertebrate host/trematode interactions : research of molecular determinants. Parasite, 2008, 15, pp.304-309. ⟨10.1051/parasite/2008153304⟩. ⟨hal-02668649⟩
  • E. Roger, Benjamin Gourbal, Christoph Grunau, R.J. Pierce, Richard Galinier, et al.. Expression analysis of highly polymorphic mucin proteins (Sm PoMuc) from the parasite Schistosoma mansoni. Molecular and Biochemical Parasitology, 2008, 157, pp.217-227. ⟨10.1016/j.molbiopara.2007.11.015⟩. ⟨halsde-00286479⟩
  • E. Roger, G. Mitta, Y. Moné, A. Bouchut, Anne Rognon, et al.. Molecular determinants of compatibility polymorphism in the Biomphalaria glabrata / Schistosoma mansoni model: New candidates identified by a global comparative proteomics approach. Molecular and Biochemical Parasitology, 2008, 157, pp.205-216. ⟨10.1016/j.molbiopara.2007.11.003⟩. ⟨halsde-00286494⟩
  • A. Bouchut, E. Roger, Benjamin Gourbal, Christoph Grunau, C. Coustau, et al.. The compatibility polymorphism in invertebrate host/trematodes interactions: research of molecular determinants. Parasite, 2008, 15 (3), pp.304-309. ⟨halsde-00344425⟩
  • François Guillou, Emmanuel Roger, Yves Moné, Anne Rognon, Benjamin E F Gourbal, et al.. Excretory-secretory proteome of larval Schistosoma mansoni and Echinostoma caproni, two parasites of Biomphalaria glabrata.. Molecular and Biochemical Parasitology, 2007, 155 (1), pp.45-56. ⟨10.1016/j.molbiopara.2007.05.009⟩. ⟨hal-00170690⟩
  • A. Bouchut, C. Coustau, Benjamin Gourbal, G. Mitta. Compatibility in the Biomphalaria glabrata/Echinostoma caproni model: new candidate genes evidenced by a suppressive subtractive hybridization approach.. Parasitology, 2007, 134 (Pt 4), pp.575-88. ⟨10.1017/S0031182006001673⟩. ⟨hal-00170741⟩
  • Baptiste Vergnes, Benjamin Gourbal, Isabelle Girard, Shyam Sundar, Jolyne Drummelsmith, et al.. A proteomics screen implicates HSP83 and a small kinetoplastid calpain-related protein in drug resistance in Leishmania donovani clinical field isolates by modulating drug-induced programmed cell death.. Molecular and Cellular Proteomics, 2007, 6 (1), pp.88-101. ⟨10.1074/mcp.M600319-MCP200⟩. ⟨hal-00170702⟩
  • Benjamin Gourbal, C. Gabrion. Histomorphological study of the preputial and clitoral glands in BALB/c mice with experimental Taenia crassiceps infections.. Journal of Parasitology, 2006, 92 (1), pp.189-92. ⟨hal-00105052⟩
  • A. Bouchut, E. Roger, C. Coustau, Benjamin Gourbal, G. Mitta. Compatibility in the Biomphalaria glabrata/Echinostoma caproni model: potential involvement of adhesion genes.. International Journal for Parasitology, 2006, 36 (2), pp.175-84. ⟨10.1016/j.ijpara.2005.09.009⟩. ⟨hal-00105033⟩
  • Nathalie Marquis, Benjamin Gourbal, Barry P. Rosen, Rita Mukhopadhyay, Marc Ouellette. Modulation in aquaglyceroporin AQP1 gene transcript levels in drug-resistant Leishmania. Molecular Microbiology, 2005, 57, pp.1690-1699. ⟨10.1111/j.1365-2958.2005.04782.x⟩. ⟨hal-00014219⟩
  • Benjamin Gourbal, André Lacroix, C. Gabrion. Behavioural dominance and Taenia crassiceps parasitism in BALB/c male mice. Parasitology Research, 2002, 88, pp.912-917. ⟨10.1007/s00436-002-0691-7⟩. ⟨hal-00192025⟩

Communications dans un congrès20 document

  • Annia Alba, Philippe Douchet, Olivier REY, D. Faugère, Joaquín López-Soriano, et al.. Alien lymnaeid snails in the Western Mediterranean basin: new invaders and trematode-transmitters in the region?. ESOVE 2024 23rd European Society for Vector Ecology Conference, Oct 2024, Montpellier, France. ⟨hal-04882379⟩
  • Nelia Luviano, Marie Lopez, Fleur Gawehns, Cristian Chaparro, Paola B Arimondo, et al.. New insights into the role of DNA methylation in Biomphalaria glabrata infection susceptibility. XVI Symposium on Schistosomiasis, FIOCRUZ, Nov 2022, Ouro Preto, Brazil. ⟨hal-03963335⟩
  • Mathilde Jaquet, Benjamin Gourbal, Antonio A. Vazquez Perera. Animation de table ronde : risque vectoriel en Occitanie (RIVOC). Congrès des doctorants de l'Université de Perpignan UPVDoc, Association des doctorants UPVDoc, Nov 2022, Perpignan, France. ⟨hal-03990857⟩
  • Annia Alba, A.A. Vázquez, J. Sanchez, Benjamin Gourbal. Lymnaeidae snails and Trematoda interaction: towards the understanding of Pseudosuccinea columella resistance to Fasciola hepatica. XXVI Congreso de la Federación Latinoamericana de Parasitología, FLAP 2022, Federación Latinoamericana de Parasitología, Nov 2022, La Havana, Cuba. ⟨hal-04886039⟩
  • Benjamin Gourbal. Epigenetic and metabolic changes in hemocytes appear as a conserved feature of innate immune memory in the Schistosomiasis vector snail Biomphalaria glabrata. ICOPA 2022 15th International Congress of Parasitology, World Federation of Parasitologists, Aug 2022, Copenhague, Denmark. ⟨hal-04886490⟩
  • Annia Alba, A.A. Vázquez, J Sanchez, Benjamin Gourbal. Resistencia de Pseudosuccinea columella (Gastropoda) a Fasciola hepatica y sus posibles orígenes: ¿selección mediada por el parásito o por el ambiente (ANNIA ALBA, INVITED SPEAKER). CLEVOL 2021Congreso Latinoamericano de Evolución, Nov 2021, Online, Francia. ⟨hal-04888673⟩
  • Remi Pichon, Silvain Pinaud, Maud Laffitte, Cristian Chaparro, Emmanuel Vignal, et al.. A Single Cell RNA sequencing approach to characterize Biomphalaria glabrata hemocyte responses in innate immune memory process. 2021 International Congress on Invertebrate Pathology & Microbial Control + 53rd Annual Meeting of the SIP (Society for Invertebrate Pathology), Society for Invertebrate Pathology, Jun 2021, Online, France. ⟨hal-04888716⟩
  • Remi Pichon, Silvain Pinaud, Manon Fallet, Celine Cosseau, Cristian Chaparro, et al.. Epigenetic and metabolomic changes in hemocytes underlie innate immune memory in the vector snail Biomphalaria glabrata. 2021 International Congress on Invertebrate Pathology & Microbial Control + 53rd Annual Meeting of the SIP (Society for Invertebrate Pathology), Society for Invertebrate Pathology, Jun 2021, Online, France. ⟨hal-04888598⟩
  • C. Montagnani, Guillaume Charrière, Delphine Destoumieux-Garzon, Benjamin Gourbal. Multifaceted escape from host immunity in Vibriospathogenic for oysters (DELPHINE DESTOUMIEUX-GARZON, INVITED SPEAKER). Ecological Immunology Workshop "Resistance tolerance and symbionts", Freie Universitât Berlin (Germany), Aug 2020, Berlin (online), Germany. ⟨hal-04889238⟩
  • Damien Lassalle, Richard Galinier, Benjamin Gourbal, David Duval. A story of the beta pore forming toxins in the fresh water snail Biomphalaria glabrata. International Congress on Invertebrate Pathology and Microbial Control / 52nd Annual Meeting of the Society for Invertebrate Pathology / 17th Meeting of the IOBC-WPRS Working Group "Microbial and Nematode Control of Invertebrate Pets" SIP/IOBC 2019, Society for Invertebrate Pathology; Working Group "Microbial and Nematode Control of Invertebrate Pets", Jul 2019, Valencia (Espagne), Spain. ⟨hal-04890405⟩
  • Benjamin Gourbal. An integrative approach of innate immune memory in the lophotrochozoan snail Biomphalaria glabrata (INVITED SPEAKER). Journée Thématique Immunité et Capacités de Défense, UMR I-02 SEBIO, Jul 2019, Reims, France. ⟨hal-04891170⟩
  • Maxime Lafont, Bruno Petton, Julien de Lorgeril, Agnès Vergnes, Jeremie Vidal-Dupiol, et al.. Efficient and long-lasting protection against the pacific oyster mortality syndrome through antiviral immune priming. 3rd International Conference of Fish & Shellfish Immunology ISFSI 2019, Jun 2019, Las Palmas, Spain. ⟨hal-04891768⟩
  • Maxime Lafont, Bruno Petton, Julien de Lorgeril, Agnes Vergnes, Jeremie Vidal-Dupiol, et al.. Efficient and long-lasting protection against the pacific oyster mortality syndrome through antiviral immune priming. 3rd Conference of the International Society of Fish & Shellfish Immunology (ISFSI), Jun 2019, Las Palmas, Spain. pp.461-461, ⟨10.1016/j.fsi.2019.04.262⟩. ⟨hal-02350814⟩
  • Camille Huot, Anaïs Portet, David Duval, Richard Galinier, Benjamin Gourbal, et al.. Microbiota structure and dynamics in planorbid snails, vector of the human parasite Schistosoma spp. REID + Immuninv 2019, Réseau Ecologie des Interactions Durables; Réseau Immunité des Invertébrés, May 2019, Montpellier, France. ⟨hal-04890528⟩
  • Silvain Pinaud, Richard Galinier, David Duval, Benjamin Gourbal. Innate immune memory, a new paradigm in invertebrate immunity: molecular bases beyond phenotypes in the vector snail Biomphalaria glabrata. REID + Immuninv 2019, Réseau Ecologie des Interactions Durables; Réseau Immunité des Invertébrés, May 2019, Montpellier, France. ⟨hal-04890511⟩
  • C. Montagnani, Maxime Lafont, Bruno Petton, Julien de Lorgeril, Manon Fallet, et al.. How to strain your oyster? A story of immune shaping and priming in the pacific oyster, Crassostrea gigas. Aqua 2018 14th International Symposium on Aquaculture Nutrition, Aug 2018, Montpellier, France. ⟨hal-03965651⟩
  • Céline Cosseau, Eve Toulza, Richard Galinier, Benjamin Gourbal, Christoph Grunau. A systems biology approach linking genetic, epigenetic, cytoplasmic and holobiont inheritance to understand rapid adaptation of parasitic flatworms (Schistosoma sp.). 66th Annual Meeting of the American Society of Tropical Medicine and Hygiene, Nov 2017, Baltimore, United States. pp.183. ⟨hal-03132820⟩
  • E. Roger, Christoph Grunau, H. Hirai, R. Pierce, Benjamin Gourbal, et al.. Le polymorphisme de mucines (SmPoMucs) au coeur de l'interaction entre B. glabrata et S. mansoni : un "chaos contrôlé". Immuninv. 2008, Apr 2008, Montpellier, France. ⟨halsde-00329916⟩
  • Y. Moné, E. Roger, Christoph Grunau, Benjamin Gourbal, G. Mitta. Déterminants moléculaires de la compatibilité dans l'interaction Biomphalaria glabrata / Schistosoma mansoni : approche protéomique comparative et caractérisation des mucines polymorphes de S. mansoni (SmPoMuc). Immuninv 2008, Apr 2008, Montpellier, France. ⟨halsde-00330460⟩
  • E. Roger, Benjamin Gourbal, Christoph Grunau, R. Pierce, G. Mitta. Des mucines polymorphes (SmPoMucs) au coeur de l'interaction entre B. glabrata et S. mansoni. Réunion annuelle du Réseau Ecologie des Interactions Durables, Jan 2008, Tours, France. ⟨halsde-00329976⟩

Poster de conférence11 document

  • Annia Alba, R Schols, A.A. Vázquez, J. Sanchez, Philippe Douchet, et al.. Microbiome and host resistance to a trematode parasite: the case of a vector snail. ESOVE 2024 23rd European Society for Vector Ecology Conference, Oct 2024, Montpellier, France. , 2024. ⟨hal-04882412⟩
  • Annia Alba, R. Schols, A.A. Vázquez, J. Sánchez, Philippe Douchet, et al.. How the environment influences the transmission of zoonotic diseases: insights on the microbiota and the vector competence of an intermediate host snail. Hydra Helminth Conference. Parasitic Helminths: New Perspectives in Biology and Infection, Sep 2023, Hydra, Greece. . ⟨hal-04884464⟩
  • Pierre Poteaux, Aline Parpinel, Benjamin Gourbal, Laurent Maveyraud, David Duval. Biomphalysins: Aerolysin-like toxins from Biomphalaria glabrata snail. Etox Meeting, Jun 2023, Perthshire, United Kingdom. ⟨hal-04884487⟩
  • Pierre Poteaux, Yonko Gorand, Benjamin Gourbal, David Duval. Serial capture of Schistosoma mansoni tegument ultrastructure during miracidium to primary sporocyst transformation. ICOPA 2022, Aug 2022, Copenhague, Denmark. . ⟨hal-03990943⟩
  • Mathilde Jaquet, Philippe Douchet, Benjamin Gourbal, Bruno Senghor, Jérôme Boissier, et al.. Schistosomiasis: Linking diet, microbiome and snail competence. ICOPA 2022 15th International Congress of Parasitology, Aug 2022, Copenhague, Denmark. . ⟨hal-04886550⟩
  • Elodie Simphor, Remi Pichon, Anne Rognon, Richard Galinier, Benjamin Gourbal, et al.. Selection of two subpopulations of Biomphalaria glabrata for their resistance and susceptibility to Schistosoma mansoni. 18th Ecology and Evolution of Infectious Diseases Meeting EEID2021, Jun 2021, Montpellier, France. . ⟨hal-04887991⟩
  • Remi Pichon, Silvain Pinaud, Maud Laffitte, Cristian Chaparro, Emmanuel Vignal, et al.. Innate immune memory process in Biomphalaria glabrata snails: a comparative multi-omic approach to decipher the function and role-played by the hemocyte immune cells against S. mansoni infections. 18th Ecology and Evolution of Infectious Diseases Meeting EEID2021, Jun 2021, Montpellier, France. . ⟨hal-04887929⟩
  • Annia Alba, J. Sanchez, Antonio Vazquez, David Duval, Cristian Chaparro, et al.. Pseudosuccinea columella – Fasciola hepatica interaction: on the mechanistic and immunobiological bases of the snail host resistance/susceptibility to its parasitic trematode. REID + Immuninv 2019, May 2019, Montpellier, France. . ⟨hal-04890610⟩
  • Damien Lassalle, Richard Galinier, Benjamin Gourbal, David Duval. New beta pore forming toxin in the freshwater snail Biomphalaria glabrata. REID + Immuninv 2019, May 2019, Montpellier, France. . ⟨hal-04890615⟩
  • Camille Huot, Anaïs Portet, David Duval, Richard Galinier, Benjamin Gourbal, et al.. Microbiota characterization in planorbids snail, vector of bilharziosis agent, Schistosoma spp. MicrobiOccitanie 2019 Congrès de Microbiologie en Occitanie, Feb 2019, Montpellier, France. . ⟨hal-04890829⟩
  • David Duval, Richard Galinier, Gabriel Mouahid, Eve Toulza, Anne Rognon, et al.. Paenibacillus, a novel pathogen of Biomphalaria glabrata, an intermediate host for schistosomiasis. ImmunInv 2014 (Colloque Immunité des Invertébrés), May 2014, Dijon, France. . ⟨hal-01134490⟩

Proceedings/Recueil des communications1 document

  • Christoph Grunau, Jérôme Boissier, Celine Cosseau, Sophie Beltran-Bech, David Duval, et al.. Schistosoma mansoni: how to make a female. American Journal of Tropical Medicine and Hygiene, 81 (5_Suppl_1), pp.51-100, 2009, ⟨10.4269/ajtmh.2009.81.51⟩. ⟨hal-04026719⟩

Chapitres d'ouvrage7 document

  • Sylvie Hurtrez-Boussès, Annia Alba, P. Alda, Elodie Chapuis, D. Faugère, et al.. Overview of interactions between parasitic Digenea and their molluscan hosts with special emphasis on lymnaeids (chapitre 12). M.V. Vinarski; A.A. Vazquez. The Lymnaeidae: natural history and parasitological significance, Springer Nature, 2023, 978-3-031-30292-3. ⟨10.1007/978-3-031-30292-3⟩. ⟨hal-04884426⟩
  • Annia Alba, Benjamin Gourbal. Biology of the Lymnaeidae – parasite interaction (chapitre 11). M.V. Vinarski; A.A. Vazquez. The Lymnaeidae: natural history and parasitological significance, Springer Nature, 2023, 978-3-031-30292-3. ⟨hal-04884434⟩
  • Yannick Moret, Christine Coustau, Christine Braquart-Varnier, Benjamin Gourbal. Immune Priming and Trans-Generational Protection From Parasites. Encyclopedia of Animal Behavior, Elsevier, pp.764-774, 2019, ⟨10.1016/B978-0-12-809633-8.90726-X⟩. ⟨hal-01976408⟩
  • Jean-Michel Escoubas, Benjamin Gourbal, David Duval, Timothy Green, Guillaume Charrière, et al.. Immunity in Molluscs. Encyclopedia of Immunobiology, Elsevier, pp.417-436, 2016, ⟨10.1016/B978-0-12-374279-7.12004-1⟩. ⟨hal-03895993⟩
  • Timothy P Yoshino, Benjamin Gourbal, André Théron. Schistosoma sporocysts (chapitre 7). Jamieson, B.G.M. Schistosoma: biology, pathology and control, CRC Press, pp.31, 2016, 978-1498744256. ⟨hal-03129822⟩
  • Benjamin Gourbal, André Théron, Christoph Grunau, David Duval, Guillaume Mitta. Polymorphic mucin-like proteins in Schistosoma mansoni, a variable antigen and a key component of the compatibility between the schistosome and its snail host. Hsu, E.; Du Pasquier, L. Pathogen-host interactions: antigenic variation v. somatic adaptations, 57, Springer, pp.91-108, 2015, Results and problems in cell differentiation, 978-3319208183. ⟨10.1007/978-3-319-20819-0_4⟩. ⟨hal-03110515⟩
  • Coen Adema, Christine Coustau, Benjamin E F Gourbal, Guillaume Mitta. Echinostomes and snails: exploring complex interactions. The biology of Echinostomes, Springer, pp.35-61, 2008, 978-0-387-09576-9. ⟨hal-00941935⟩

Pré-publications, Documents de travail4 document

  • Mathilde J Jaquet, Philippe Douchet, Eve Toulza, Thierry Lefevre, Bruno Senghor, et al.. Evidences that host genetic background more than the environment shapes the microbiota of the snail Bulinus truncatus , an intermediate host of Schistosoma species. 2025. ⟨hal-04879778⟩
  • Sébastien de la Forest Divonne, Juliette Pouzadoux, Océane Romatif, C. Montagnani, Guillaume Mitta, et al.. Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations. 2024. ⟨hal-04782332⟩
  • Jean Luc Rolland, Estelle Masseret, Mohamed Laabir, Guillaume Tetreau, Benjamin Gourbal, et al.. Starvation of the bacteria Vibrio atlanticus promotes lightning group-attacks on the dinoflagellate Alexandrium pacificum. 2024. ⟨hal-04879695⟩
  • Anaïs Portet, Eve Toulza, Ana Lokmer, Camille Huot, David Duval, et al.. Infection of the Biomphalaria glabrata vector snail by Schistosoma mansoni parasites drives snail microbiota dysbiosis. 2018. ⟨hal-03134818⟩

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